Difference between revisions of "YDR381W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:1236551..1237997
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|nowrap| Chr IV:1236558..1238004
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002789
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002789

Revision as of 14:05, 3 February 2011

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Systematic name YDR381W
Gene name YRA1
Aliases SHE11
Feature type ORF, Verified
Coordinates Chr IV:1236558..1238004
Primary SGDID S000002789


Description of YDR381W: RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; functionally redundant with Yra2p, another REF family member[1][2][3][4]




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References

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  1. Johnson SA, et al. (2009) Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11. Mol Cell 33(2):215-26 SGD PMID 19110458
  2. Portman DS, et al. (1997) YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity. RNA 3(5):527-37 SGD PMID 9149233
  3. Strasser K and Hurt E (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J 19(3):410-20 SGD PMID 10722314
  4. Zenklusen D, et al. (2001) The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p. Mol Cell Biol 21(13):4219-32 SGD PMID 11390651

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