Difference between revisions of "YDR381W"
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| − | '''Description of YDR381W:''' | + | '''Description of YDR381W:''' RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; functionally redundant with Yra2p, another REF family member<ref name='S000052851'>Portman DS, et al. (1997) YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity. RNA 3(5):527-37 {{SGDpaper|S000052851}} PMID 9149233</ref><ref name='S000061447'>Zenklusen D, et al. (2001) The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p. Mol Cell Biol 21(13):4219-32 {{SGDpaper|S000061447}} PMID 11390651</ref><ref name='S000064041'>Strasser K and Hurt E (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J 19(3):410-20 {{SGDpaper|S000064041}} PMID 10722314</ref><ref name='S000128735'>Johnson SA, et al. (2009) Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11. Mol Cell 33(2):215-26 |
| − | {{SGDpaper| | + | {{SGDpaper|S000128735}} PMID 19110458</ref> |
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Revision as of 14:05, 4 January 2010
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| Systematic name | YDR381W |
| Gene name | YRA1 |
| Aliases | SHE11 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1236551..1237997 |
| Primary SGDID | S000002789 |
Description of YDR381W: RNA binding protein required for export of poly(A)+ mRNA from the nucleus; proposed to couple mRNA export with 3' end processing via its interactions with Mex67p and Pcf11p; functionally redundant with Yra2p, another REF family member[1][2][3][4]
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References
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- ↑ Portman DS, et al. (1997) YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity. RNA 3(5):527-37 SGD PMID 9149233
- ↑ Zenklusen D, et al. (2001) The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p. Mol Cell Biol 21(13):4219-32 SGD PMID 11390651
- ↑ Strasser K and Hurt E (2000) Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export. EMBO J 19(3):410-20 SGD PMID 10722314
- ↑ Johnson SA, et al. (2009) Cotranscriptional recruitment of the mRNA export factor Yra1 by direct interaction with the 3' end processing factor Pcf11. Mol Cell 33(2):215-26 SGD PMID 19110458
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