Difference between revisions of "YDR372C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS74 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''VPS74 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''API1''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''API1, MNN3''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]

Revision as of 14:05, 19 October 2010

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Systematic name YDR372C
Gene name VPS74
Aliases API1, MNN3
Feature type ORF, Verified
Coordinates Chr IV:1222142..1221105
Primary SGDID S000002780


Description of YDR372C: Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; binding to PtdIns4P required for Golgi targeting and function; tetramer formation required for function[1][2]




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References

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  1. Schmitz KR, et al. (2008) Golgi localization of glycosyltransferases requires a Vps74p oligomer. Dev Cell 14(4):523-34 SGD PMID 18410729
  2. Wood CS, et al. (2009) PtdIns4P recognition by Vps74/GOLPH3 links PtdIns 4-kinase signaling to retrograde Golgi trafficking. J Cell Biol 187(7):967-75 SGD PMID 20026658

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