YDR369C

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Systematic name YDR369C
Gene name XRS2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1217572..1215008


Description of YDR369C: Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling[1][2][3]




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Interactions

Two Hybrid

Two Hybrid interaction with Rec107
[4] [5]


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References

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  1. Usui T, et al. (1998) Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell 95(5):705-16 SGD PMID 9845372
  2. Bressan DA, et al. (1999) The Mre11-Rad50-Xrs2 protein complex facilitates homologous recombination-based double-strand break repair in Saccharomyces cerevisiae. Mol Cell Biol 19(11):7681-7 SGD PMID 10523656
  3. Ivanov EL, et al. (1992) XRS2, a DNA repair gene of Saccharomyces cerevisiae, is needed for meiotic recombination. Genetics 132(3):651-64 SGD PMID 1468624
  4. Arora C, et al. (2004) Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell 13(4):549-59 SGD PMID 14992724
  5. submitted by Scott Keeney on 2004-05-02

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