Difference between revisions of "YDR363W"

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'''Description of YDR363W:''' Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins<ref name='S000071547'>Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 {{SGDpaper|S000071547}} PMID 12399377</ref><ref name='S000056456'>Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80
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'''Description of YDR363W:''' Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins<ref name='S000128989'>Mankouri HW, et al. (2009) Esc2 and Sgs1 Act in Functionally Distinct Branches of the Homologous Recombination Repair Pathway in S. cerevisiae. Mol Biol Cell {{SGDpaper|S000128989}} PMID 19158388</ref><ref name='S000080832'>Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6:22 {{SGDpaper|S000080832}} PMID 15698469</ref><ref name='S000071547'>Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 {{SGDpaper|S000071547}} PMID 12399377</ref><ref name='S000056456'>Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80
 
  {{SGDpaper|S000056456}} PMID 11090616</ref>
 
  {{SGDpaper|S000056456}} PMID 11090616</ref>
 
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Revision as of 14:05, 30 January 2009

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Systematic name YDR363W
Gene name ESC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1199176..1200546
Primary SGDID S000002771


Description of YDR363W: Protein involved in silencing; may recruit or stabilize Sir proteins; role in Rad51-dependent homologous recombination repair and intra S-phase DNA damage checkpoint; member of the RENi (Rad60-Esc2-Nip45) family of SUMO-like domain proteins[1][2][3][4]




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References

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  1. Mankouri HW, et al. (2009) Esc2 and Sgs1 Act in Functionally Distinct Branches of the Homologous Recombination Repair Pathway in S. cerevisiae. Mol Biol Cell SGD PMID 19158388
  2. Novatchkova M, et al. (2005) Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family. BMC Bioinformatics 6:22 SGD PMID 15698469
  3. Cuperus G and Shore D (2002) Restoration of silencing in Saccharomyces cerevisiae by tethering of a novel Sir2-interacting protein, Esc8. Genetics 162(2):633-45 SGD PMID 12399377
  4. Dhillon N and Kamakaka RT (2000) A histone variant, Htz1p, and a Sir1p-like protein, Esc2p, mediate silencing at HMR. Mol Cell 6(4):769-80 SGD PMID 11090616

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