YDR339C

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Systematic name YDR339C
Gene name FCF1
Aliases UTP24
Feature type ORF, Verified
Coordinates Chr IV:1150515..1149946
Primary SGDID S000002747


Description of YDR339C: Putative PINc domain nuclease required for early cleavages of 35S pre-rRNA and maturation of 18S rRNA; component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; copurifies with Faf1p[1][2]




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References

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  1. Rempola B, et al. (2006) Fcf1p and Fcf2p are novel nucleolar Saccharomyces cerevisiae proteins involved in pre-rRNA processing. Biochem Biophys Res Commun 346(2):546-54 SGD PMID 16762320
  2. Bleichert F, et al. (2006) The PINc domain protein Utp24, a putative nuclease, is required for the early cleavage steps in 18S rRNA maturation. Proc Natl Acad Sci U S A 103(25):9464-9 SGD PMID 16769905

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