YDR325W

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Systematic name YDR325W
Gene name YCG1
Aliases TIE1, YCS5
Feature type ORF, Verified
Coordinates Chr IV:1117121..1120228


Description of YDR325W: Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation and for chromatin binding of the condensin complex[1][2][3]




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References

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  1. Lavoie BD, et al. (2002) In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J Cell Biol 156(5):805-15 SGD PMID 11864994
  2. Ouspenski II, et al. (2000) Chromosome condensation factor Brn1p is required for chromatid separation in mitosis. Mol Biol Cell 11(4):1305-13 SGD PMID 10749931
  3. Freeman L, et al. (2000) The condensin complex governs chromosome condensation and mitotic transmission of rDNA. J Cell Biol 149(4):811-24 SGD PMID 10811823

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