YDR325W

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Systematic name YDR325W
Gene name YCG1
Aliases TIE1, YCS5
Feature type ORF, Verified
Coordinates Chr IV:1117122..1120229
Primary SGDID S000002733


Description of YDR325W: Non-SMC subunit of the condensin complex; required for establishment and maintenance of chromosome condensation, chromosome segregation and chromatin binding of the condensin complex; required for clustering of tRNA genes at the nucleolus[1][2][3][4]




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References

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  1. Haeusler RA, et al. (2008) Clustering of yeast tRNA genes is mediated by specific association of condensin with tRNA gene transcription complexes. Genes Dev 22(16):2204-14 SGD PMID 18708579
  2. Lavoie BD, et al. (2002) In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin. J Cell Biol 156(5):805-15 SGD PMID 11864994
  3. Ouspenski II, et al. (2000) Chromosome condensation factor Brn1p is required for chromatid separation in mitosis. Mol Biol Cell 11(4):1305-13 SGD PMID 10749931
  4. Freeman L, et al. (2000) The condensin complex governs chromosome condensation and mitotic transmission of rDNA. J Cell Biol 149(4):811-24 SGD PMID 10811823

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