YDR321W

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Systematic name YDR321W
Gene name ASP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1108702..1109847
Primary SGDID S000002729


Description of YDR321W: Cytosolic L-asparaginase, involved in asparagine catabolism; catalyzes hydrolysis of L-asparagine to aspartic acid and ammonia, has an important role in therapy of acute lymphoblastic leukemia; synthesized constitutively[1][2]




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References

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  1. Cooper TG (1982) Nitrogen metabolism in Saccharomyces cerevisiae. Pp. 39-99 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
  2. Sinclair K, et al. (1994) The ASP1 gene of Saccharomyces cerevisiae, encoding the intracellular isozyme of L-asparaginase. Gene 144(1):37-43 SGD PMID 8026756

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