Difference between revisions of "YDR293C"
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| − | + | Strain W303 has ''ssd1-d2'' allele<ref>Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48</ref> in which the 2094th nucleotide C is substituted with G, resulting in a premature stop codon<ref>Jorgensen et al. (2002) High-Resolution Genetic Mapping With Ordered Arrays of Saccharomyces cerevisiae Deletion Mutants. Genetics 162(3):1091-9</ref>, whereas S288C and BY4741 strains have dominant ''SSD1-V''<ref>Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48</ref>, which encodes a full-length Ssd1 protein. | |
| + | --[[User:S.hiraga|S.hiraga]] 16:19, 29 April 2010 (UTC) | ||
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==References== | ==References== | ||
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Revision as of 09:19, 29 April 2010
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR293C |
| Gene name | SSD1 |
| Aliases | CLA1, MCS1, RLT1, SRK1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1049389..1045637 |
| Primary SGDID | S000002701 |
Description of YDR293C: Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence[1][2][3]
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Contents
Community Commentary
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Strain W303 has ssd1-d2 allele[4] in which the 2094th nucleotide C is substituted with G, resulting in a premature stop codon[5], whereas S288C and BY4741 strains have dominant SSD1-V[6], which encodes a full-length Ssd1 protein.
--S.hiraga 16:19, 29 April 2010 (UTC)
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References
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- ↑ Kaeberlein M and Guarente L (2002) Saccharomyces cerevisiae MPT5 and SSD1 function in parallel pathways to promote cell wall integrity. Genetics 160(1):83-95 SGD PMID 11805047
- ↑ Reinke A, et al. (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62 SGD PMID 14736892
- ↑ Wheeler RT, et al. (2003) A Saccharomyces cerevisiae mutant with increased virulence. Proc Natl Acad Sci U S A 100(5):2766-70 SGD PMID 12589024
- ↑ Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48
- ↑ Jorgensen et al. (2002) High-Resolution Genetic Mapping With Ordered Arrays of Saccharomyces cerevisiae Deletion Mutants. Genetics 162(3):1091-9
- ↑ Sutton et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48
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