Difference between revisions of "YDR277C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002685 YDR277C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002685 YDR277C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MTH1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MTH1 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YDR277C
Gene name MTH1
Aliases BPC1, DGT1, HTR1
Feature type ORF, Verified
Coordinates Chr IV:1015702..1014401
Primary SGDID S000002685


Description of YDR277C: Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation[1][2][3]




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References

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  1. Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72 SGD PMID 10632886
  2. Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 SGD PMID 14508605
  3. Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7 SGD PMID 14755054

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