Difference between revisions of "YDR265W"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
(Automated import of articles)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
Line 13: Line 14:
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr IV:998860..999873
 
|nowrap| Chr IV:998860..999873
|-
 
|colspan = '3'|{{Don'tEditThisBox}}
 
 
|}
 
|}
 
<br>
 
<br>
Line 23: Line 22:
 
<br>
 
<br>
 
<br>
 
<br>
 +
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
Line 35: Line 36:
  
 
{{ShortCenteredHR}}
 
{{ShortCenteredHR}}
 +
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Revision as of 08:17, 30 January 2007

Share your knowledge...Edit this entry! <protect>

Systematic name YDR265W
Gene name PEX10
Aliases PAS4
Feature type ORF, Verified
Coordinates Chr IV:998860..999873


Description of YDR265W: RING finger peroxisomal membrane peroxin required for peroxisomal matrix protein import, interacts with Pex12p, links ubiquitin-conjugating Pex4p to protein import machinery; mutations in human homolog cause a variety of peroxisomal disorders[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Other Protein Details

Other Topic: Homology

Homology was found, at the sequence and domain-composition level, between several components of the Peroxisomal protein import machinery and components of the Endoplasmic Reticulum Associated Decay (ERAD) pathway. This suggests a common evolutionary origin for both systems and a similar mechanism of action. The homology relationships can be stablished between Pex1,Pex6 and cdc48; Pex2 and Hrd1; Pex4 and Ubc1; and Pex5 and Hrd3. [5] [6]


<protect>

References

See Help:References on how to add references

  1. Eckert JH and Johnsson N (2003) Pex10p links the ubiquitin conjugating enzyme Pex4p to the protein import machinery of the peroxisome. J Cell Sci 116(Pt 17):3623-34 SGD PMID 12876220
  2. Purdue PE and Lazarow PB (2001) Peroxisome biogenesis. Annu Rev Cell Dev Biol 17():701-52 SGD PMID 11687502
  3. Albertini M, et al. (2001) Pex12p of Saccharomyces cerevisiae is a component of a multi-protein complex essential for peroxisomal matrix protein import. Eur J Cell Biol 80(4):257-70 SGD PMID 11370741
  4. Warren DS, et al. (1998) Identification of PEX10, the gene defective in complementation group 7 of the peroxisome-biogenesis disorders. Am J Hum Genet 63(2):347-59 SGD PMID 9683594
  5. Gabaldon T, et al. (2006) Origin and evolution of the peroxisomal proteome. Biol Direct 1():8 SGD PMID 16556314
  6. submitted by Toni Gabaldon on 2006-04-12

See Help:Categories on how to add the wiki page for this gene to a Category </protect>