Difference between revisions of "YDR254W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002662 YDR254W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CHL4 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''CHL4 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:965113..966489 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002662 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002662 | ||
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| − | '''Description of YDR254W:''' Outer kinetochore protein required for chromosome stability; involved in new kinetochore assembly and sister chromatid cohesion; peripheral component of the Ctf19 kinetochore | + | '''Description of YDR254W:''' Outer kinetochore protein required for chromosome stability; involved in new kinetochore assembly and sister chromatid cohesion; peripheral component of the Ctf19 kinetochore complex that interacts with Ctf19p, Ctf3p, Iml3p and Mif2p; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-N and fission yeast mis15<ref name='S000131456'>Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 {{SGDpaper|S000131456}} PMID 19730685</ref><ref name='S000049369'>Kouprina NYu, et al. (1988) Genetic control of chromosome stability in the yeast Saccharomyces cerevisiae. Yeast 4(4):257-69 {{SGDpaper|S000049369}} PMID 3064490</ref><ref name='S000075612'>Marston AL, et al. (2004) A genome-wide screen identifies genes required for centromeric cohesion. Science 303(5662):1367-70 {{SGDpaper|S000075612}} PMID 14752166</ref><ref name='S000072780'>Mythreye K and Bloom KS (2003) Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J Cell Biol 160(6):833-43 {{SGDpaper|S000072780}} PMID 12642611</ref><ref name='S000074151'>Pot I, et al. (2003) Chl4p and iml3p are two new members of the budding yeast outer kinetochore. Mol Biol Cell 14(2):460-76 {{SGDpaper|S000074151}} PMID 12589047</ref><ref name='S000149670'>Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 |
| − | {{SGDpaper| | + | {{SGDpaper|S000149670}} PMID 22561346</ref> |
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Latest revision as of 14:05, 9 October 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDR254W |
| Gene name | CHL4 |
| Aliases | CTF17, MCM17 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:965113..966489 |
| Primary SGDID | S000002662 |
Description of YDR254W: Outer kinetochore protein required for chromosome stability; involved in new kinetochore assembly and sister chromatid cohesion; peripheral component of the Ctf19 kinetochore complex that interacts with Ctf19p, Ctf3p, Iml3p and Mif2p; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-N and fission yeast mis15[1][2][3][4][5][6]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [7] [8]
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References
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- ↑ Fernius J and Marston AL (2009) Establishment of cohesion at the pericentromere by the Ctf19 kinetochore subcomplex and the replication fork-associated factor, Csm3. PLoS Genet 5(9):e1000629 SGD PMID 19730685
- ↑ Kouprina NYu, et al. (1988) Genetic control of chromosome stability in the yeast Saccharomyces cerevisiae. Yeast 4(4):257-69 SGD PMID 3064490
- ↑ Marston AL, et al. (2004) A genome-wide screen identifies genes required for centromeric cohesion. Science 303(5662):1367-70 SGD PMID 14752166
- ↑ Mythreye K and Bloom KS (2003) Differential kinetochore protein requirements for establishment versus propagation of centromere activity in Saccharomyces cerevisiae. J Cell Biol 160(6):833-43 SGD PMID 12642611
- ↑ Pot I, et al. (2003) Chl4p and iml3p are two new members of the budding yeast outer kinetochore. Mol Biol Cell 14(2):460-76 SGD PMID 12589047
- ↑ Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 SGD PMID 22561346
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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