YDR244W

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Systematic name YDR244W
Gene name PEX5
Aliases PAS10
Feature type ORF, Verified
Coordinates Chr IV:950559..952397
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Description of YDR244W: Peroxisomal membrane signal receptor for C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import, tetratricopeptide repeat protein, also involved in PTS1-independent import[1][2][3][4][5]



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References

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  1. Klein AT, et al. (2002) Saccharomyces cerevisiae acyl-CoA oxidase follows a novel, non-PTS1, import pathway into peroxisomes that is dependent on Pex5p. J Biol Chem 277(28):25011-9 SGD PMID 11967269
  2. Van der Leij I, et al. (1993) PAS10 is a tetratricopeptide-repeat protein that is essential for the import of most matrix proteins into peroxisomes of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 90(24):11782-6 SGD PMID 8265627
  3. Fransen M, et al. (1995) Identification and characterization of the putative human peroxisomal C-terminal targeting signal import receptor. J Biol Chem 270(13):7731-6 SGD PMID 7706321
  4. Erdmann R and Blobel G (1996) Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor. J Cell Biol 135(1):111-21 SGD PMID 8858167
  5. Brocard C, et al. (1994) The tetratricopeptide repeat-domain of the PAS10 protein of Saccharomyces cerevisiae is essential for binding the peroxisomal targeting signal-SKL. Biochem Biophys Res Commun 204(3):1016-22 SGD PMID 7980572

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