Difference between revisions of "YDR217C"
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| + | === Alleles, Strains, and Phenotypes === | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
| + | ==== Multiple Knockout Strains ==== | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]] | ||
| + | '''Together with''': DCC1, CTF8<br> | ||
| + | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
| + | ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | '''Together with''': DCC1, CTF8<br> | ||
| + | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
| + | |||
| + | dcc1∆ rad9∆ double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
| + | |||
| + | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-21'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-21</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
__TOC__ | __TOC__ | ||
==Community Commentary== | ==Community Commentary== | ||
{{CommentaryHelp}} | {{CommentaryHelp}} | ||
| + | === Alleles, Strains, and Phenotypes === | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes]] | ||
| + | ==== Multiple Knockout Strains ==== | ||
| + | [[Category:Topic:Alleles, Strains, and Phenotypes:Multiple Knockout Strains]] | ||
| + | '''Together with''': DCC1, CTF8<br> | ||
| + | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
| + | |||
| + | ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | '''Together with''': DCC1, CTF8<br> | ||
| + | '''Phenotype(s)''': Viable [[Category:Phenotype:Viable]] | ||
| + | |||
| + | dcc1∆ rad9∆ double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. <ref name='S000114451'>Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 {{SGDpaper|S000114451}} PMID 16487579</ref> <ref name = 'CAset6827-2006-06-20'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=6827 Shin-ichiro Hiraga] on 2006-06-20</ref> | ||
| + | |||
| + | {{ShortCenteredHR}} | ||
| + | === Protein Details === | ||
| + | [[Category:Topic:Protein Details]] | ||
| + | ==== Protein Modification ==== | ||
| + | [[Category:Topic:Protein Details:Protein Modification]] | ||
| + | '''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]] | ||
| + | |||
| + | Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-21'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-21</ref> | ||
| + | {{ShortCenteredHR}} | ||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
Revision as of 17:05, 23 January 2007
Share your knowledge...Edit this entry!
| Systematic name | YDR217C | |
| Gene name | RAD9 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr IV:903476..899547 | |
| Don't edit this box! It's automatically regenerated, and edits will be lost when the update script runs. | ||
Description of YDR217C: DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate[1][2]
Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Together with: DCC1, CTF8
Phenotype(s): Viable
ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. [3] [4]
Together with: DCC1, CTF8
Phenotype(s): Viable
dcc1∆ rad9∆ double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [3] [4]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [5]
Contents
Community Commentary
About Community Commentary. Please share your knowledge!
Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Together with: DCC1, CTF8
Phenotype(s): Viable
ctf8 rad9 double deletion strain is defective in phosphorulation of Rad53p in responce to HU and MMS. [3] [4]
Together with: DCC1, CTF8
Phenotype(s): Viable
dcc1∆ rad9∆ double deletion strain is defective in phosphorylation of Rad53p and shows higher sensitivity to HU and MMS than WT and single mutant strains. [3] [4]
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [5]
References
See Help:References on how to add references
- ↑ 1.0 1.1 1.2 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Toh GW and Lowndes NF (2003) Role of the Saccharomyces cerevisiae Rad9 protein in sensing and responding to DNA damage. Biochem Soc Trans 31(Pt 1):242-6 SGD PMID 12546694
- ↑ 3.0 3.1 3.2 3.3 Pan X, et al. (2006) A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell 124(5):1069-81 SGD PMID 16487579
- ↑ 4.0 4.1 4.2 4.3 submitted by Shin-ichiro Hiraga on 2006-06-20
- ↑ 5.0 5.1 submitted by Jeff Ubersax on 2004-01-21
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