YDR190C

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Systematic name YDR190C
Gene name RVB1
Aliases TIH1, TIP48, TIP49A
Feature type ORF, Verified
Coordinates Chr IV:841993..840602
Primary SGDID S000002598


Description of YDR190C: Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as pontin; member of the RUVB-like protein family[1][2][3][4]




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References

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  1. Qiu XB, et al. (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93 SGD PMID 9774387
  2. Jonsson ZO, et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88 SGD PMID 11278922
  3. Jonsson ZO, et al. (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77 SGD PMID 15525518
  4. Torreira E, et al. (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20 SGD PMID 18940606

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