Difference between revisions of "YDR190C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002598 YDR190C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002598 YDR190C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RVB1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''RVB1 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''TIH1, TIP48, TIP49A''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''TIH1, TIP49, TIP49A''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:841993..840602
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|nowrap| Chr IV:841995..840604
 
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|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002598
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002598
 
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'''Description of YDR190C:''' Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; also referred to as pontin; member of the RUVB-like protein family<ref name='S000128116'>Torreira E, et al. (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20 {{SGDpaper|S000128116}} PMID 18940606</ref><ref name='S000079913'>Jonsson ZO, et al. (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77 {{SGDpaper|S000079913}} PMID 15525518</ref><ref name='S000060643'>Jonsson ZO, et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88 {{SGDpaper|S000060643}} PMID 11278922</ref><ref name='S000058375'>Qiu XB, et al. (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93
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'''Description of YDR190C:''' ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly<ref name='S000125377'>Gribun A, et al. (2008) Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. J Mol Biol 376(5):1320-33 {{SGDpaper|S000125377}} PMID 18234224</ref><ref name='S000060643'>Jonsson ZO, et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88 {{SGDpaper|S000060643}} PMID 11278922</ref><ref name='S000079913'>Jonsson ZO, et al. (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77 {{SGDpaper|S000079913}} PMID 15525518</ref><ref name='S000146871'>Kakihara Y and Houry WA (2011) The R2TP complex: Discovery and functions. Biochim Biophys Acta () {{SGDpaper|S000146871}} PMID 21925213</ref><ref name='S000066250'>King TH, et al. (2001) A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins. Mol Cell Biol 21(22):7731-46 {{SGDpaper|S000066250}} PMID 11604509</ref><ref name='S000075430'>Krogan NJ, et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76 {{SGDpaper|S000075430}} PMID 14690608</ref><ref name='S000074662'>Mizuguchi G, et al. (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8 {{SGDpaper|S000074662}} PMID 14645854</ref><ref name='S000058375'>Qiu XB, et al. (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93 {{SGDpaper|S000058375}} PMID 9774387</ref><ref name='S000040657'>Shen X, et al. (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406(6795):541-4 {{SGDpaper|S000040657}} PMID 10952318</ref><ref name='S000128116'>Torreira E, et al. (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20 {{SGDpaper|S000128116}} PMID 18940606</ref><ref name='S000081009'>Zhao R, et al. (2005) Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Cell 120(5):715-27 {{SGDpaper|S000081009}} PMID 15766533</ref><ref name='S000136091'>Zhao R, et al. (2008) Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol 180(3):563-78
  {{SGDpaper|S000058375}} PMID 9774387</ref>
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  {{SGDpaper|S000136091}} PMID 18268103</ref>
 
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Latest revision as of 14:05, 6 March 2012

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Systematic name YDR190C
Gene name RVB1
Aliases TIH1, TIP49, TIP49A
Feature type ORF, Verified
Coordinates Chr IV:841995..840604
Primary SGDID S000002598


Description of YDR190C: ATP-dependent DNA helicase, also known as pontin; member of the AAA+ and RuvB-like protein families; similar to Rvb2p; conserved component of multiple complexes including the INO80 complex, the Swr1 complex, and the R2TP complex (Rvb1-Rvb2-Tah1-Pih1); involved in multiple processes such as chromatin remodeling, box C/D snoRNP assembly, and RNA polymerase II assembly[1][2][3][4][5][6][7][8][9][10][11][12]




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References

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  1. Gribun A, et al. (2008) Yeast Rvb1 and Rvb2 are ATP-dependent DNA helicases that form a heterohexameric complex. J Mol Biol 376(5):1320-33 SGD PMID 18234224
  2. Jonsson ZO, et al. (2001) Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genes. J Biol Chem 276(19):16279-88 SGD PMID 11278922
  3. Jonsson ZO, et al. (2004) Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complex. Mol Cell 16(3):465-77 SGD PMID 15525518
  4. Kakihara Y and Houry WA (2011) The R2TP complex: Discovery and functions. Biochim Biophys Acta () SGD PMID 21925213
  5. King TH, et al. (2001) A well-connected and conserved nucleoplasmic helicase is required for production of box C/D and H/ACA snoRNAs and localization of snoRNP proteins. Mol Cell Biol 21(22):7731-46 SGD PMID 11604509
  6. Krogan NJ, et al. (2003) A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1. Mol Cell 12(6):1565-76 SGD PMID 14690608
  7. Mizuguchi G, et al. (2004) ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex. Science 303(5656):343-8 SGD PMID 14645854
  8. Qiu XB, et al. (1998) An eukaryotic RuvB-like protein (RUVBL1) essential for growth. J Biol Chem 273(43):27786-93 SGD PMID 9774387
  9. Shen X, et al. (2000) A chromatin remodelling complex involved in transcription and DNA processing. Nature 406(6795):541-4 SGD PMID 10952318
  10. Torreira E, et al. (2008) Architecture of the pontin/reptin complex, essential in the assembly of several macromolecular complexes. Structure 16(10):1511-20 SGD PMID 18940606
  11. Zhao R, et al. (2005) Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Cell 120(5):715-27 SGD PMID 15766533
  12. Zhao R, et al. (2008) Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation. J Cell Biol 180(3):563-78 SGD PMID 18268103

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