YDR142C

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Systematic name YDR142C
Gene name PEX7
Aliases PAS7, PEB1
Feature type ORF, Verified
Coordinates Chr IV:741597..740470
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Description of YDR142C: Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)[1][2][3]



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References

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  1. Purdue PE, et al. (1998) Pex18p and Pex21p, a novel pair of related peroxins essential for peroxisomal targeting by the PTS2 pathway. J Cell Biol 143(7):1859-69 SGD PMID 9864360
  2. Erdmann R and Blobel G (1996) Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor. J Cell Biol 135(1):111-21 SGD PMID 8858167
  3. Zhang JW and Lazarow PB (1995) PEB1 (PAS7) in Saccharomyces cerevisiae encodes a hydrophilic, intra-peroxisomal protein that is a member of the WD repeat family and is essential for the import of thiolase into peroxisomes. J Cell Biol 129(1):65-80 SGD PMID 7535304

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