Difference between revisions of "YDR123C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR123C YDR123C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002530 YDR123C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''INO2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''INO2 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
−
|nowrap| Chr IV:699465..698551
+
|nowrap| Chr IV:699468..698554
 
|-
 
|-
−
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002530
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of {{PAGENAME}}:''' Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion<ref name='S000059049'>Gardenour KR, et al. (2004) Identification of novel dominant INO2c mutants with an Opi- phenotype. Mol Microbiol 52(5):1271-80 {{SGDpaper|S000059049}} PMID 15165231</ref><ref name='S000053926'>Ambroziak J and Henry SA (1994) INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter. J Biol Chem 269(21):15344-9 {{SGDpaper|S000053926}} PMID 8195172</ref><ref name='S000053264'>Hammond CL, et al. (1993) INO2, a regulatory gene in yeast phospholipid biosynthesis, affects nuclear segregation and bud pattern formation. Cell Mol Biol Res 39(6):561-77 {{SGDpaper|S000053264}} PMID 8012448</ref><ref name='S000046524'>Schuller HJ, et al. (1995) DNA binding site of the yeast heteromeric Ino2p/Ino4p basic helix-loop-helix transcription factor: structural requirements as defined by saturation mutagenesis. FEBS Lett 370(1-2):149-52
+
'''Description of YDR123C:''' Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion<ref name='S000053926'>Ambroziak J and Henry SA (1994) INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter. J Biol Chem 269(21):15344-9 {{SGDpaper|S000053926}} PMID 8195172</ref><ref name='S000059049'>Gardenour KR, et al. (2004) Identification of novel dominant INO2c mutants with an Opi- phenotype. Mol Microbiol 52(5):1271-80 {{SGDpaper|S000059049}} PMID 15165231</ref><ref name='S000053264'>Hammond CL, et al. (1993) INO2, a regulatory gene in yeast phospholipid biosynthesis, affects nuclear segregation and bud pattern formation. Cell Mol Biol Res 39(6):561-77 {{SGDpaper|S000053264}} PMID 8012448</ref><ref name='S000046524'>Schuller HJ, et al. (1995) DNA binding site of the yeast heteromeric Ino2p/Ino4p basic helix-loop-helix transcription factor: structural requirements as defined by saturation mutagenesis. FEBS Lett 370(1-2):149-52
 
  {{SGDpaper|S000046524}} PMID 7649294</ref>
 
  {{SGDpaper|S000046524}} PMID 7649294</ref>
 
<br>
 
<br>
Line 23: Line 24:
 
<br>
 
<br>
 
<br>
 
<br>
−
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
 +
=== Protein Details ===
 +
[[Category:Topic:Protein Details]]
 +
==== Protein Modification ====
 +
[[Category:Topic:Protein Details:Protein Modification]]
 +
'''Modification(s)''': Phosphorylation [[Category:Modification:Phosphorylation]]
 +
 +
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. <ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref> <ref name = 'CAset7903-2004-01-21'>submitted by [http://db.yeastgenome.org/cgi-bin/colleague/colleagueSearch?id=7903 Jeff Ubersax] on 2004-01-21</ref>
 +
 +
{{ShortCenteredHR}}
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
  
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 07:45, 23 January 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YDR123C
Gene name INO2
Aliases DIE1, SCS1
Feature type ORF, Verified
Coordinates Chr IV:699468..698554
Primary SGDID S000002530


Description of YDR123C: Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]




<protect>

References

See Help:References on how to add references

  1. ↑ Ambroziak J and Henry SA (1994) INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter. J Biol Chem 269(21):15344-9 SGD PMID 8195172
  2. ↑ Gardenour KR, et al. (2004) Identification of novel dominant INO2c mutants with an Opi- phenotype. Mol Microbiol 52(5):1271-80 SGD PMID 15165231
  3. ↑ Hammond CL, et al. (1993) INO2, a regulatory gene in yeast phospholipid biosynthesis, affects nuclear segregation and bud pattern formation. Cell Mol Biol Res 39(6):561-77 SGD PMID 8012448
  4. ↑ Schuller HJ, et al. (1995) DNA binding site of the yeast heteromeric Ino2p/Ino4p basic helix-loop-helix transcription factor: structural requirements as defined by saturation mutagenesis. FEBS Lett 370(1-2):149-52 SGD PMID 7649294
  5. ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. ↑ submitted by Jeff Ubersax on 2004-01-21

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YDR123C&oldid=346761"