YDR097C

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Systematic name YDR097C
Gene name MSH6
Aliases PMS3
Feature type ORF, Verified
Coordinates Chr IV:643834..640106
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Description of YDR097C: Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p[1][2][3]



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References

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  1. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  2. Bowers J, et al. (1999) A mutation in the MSH6 subunit of the Saccharomyces cerevisiae MSH2-MSH6 complex disrupts mismatch recognition. J Biol Chem 274(23):16115-25 SGD PMID 10347163
  3. Marsischky GT, et al. (1996) Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev 10(4):407-20 SGD PMID 8600025

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