Difference between revisions of "YDR081C"

From SGD-Wiki
Jump to: navigation, search
(Automated import of articles)
 
(Automated import of articles)
 
(11 intermediate revisions by the same user not shown)
Line 1: Line 1:
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
<!-- PLEASE DO NOT EDIT HERE. USE THE SECTION EDIT LINKS ON THE RIGHT MARGIN-->
 
{{PageTop}}
 
{{PageTop}}
 +
<protect>
 
{|{{Prettytable}} align = 'right' width = '200px'
 
{|{{Prettytable}} align = 'right' width = '200px'
 
|-
 
|-
−
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDR081C YDR081C]  
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002488 YDR081C]  
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PDC2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PDC2 ''
Line 12: Line 13:
 
|-
 
|-
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
−
|nowrap| Chr IV:610078..607301
+
|nowrap| Chr IV:610081..607304
 
|-
 
|-
−
|colspan = '3'|{{Don'tEditThisBox}}
+
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002488
 
|}
 
|}
 
<br>
 
<br>
−
'''Description of {{PAGENAME}}:''' Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes<ref name='S000055265'>Kaiser B, et al. (1999) Identification of a gene encoding the pyruvate decarboxylase gene regulator CaPdc2p from Candida albicans. Yeast 15(7):585-91 {{SGDpaper|S000055265}} PMID 10341421</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
+
'''Description of YDR081C:''' Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions<ref name='S000050008'>Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 {{SGDpaper|S000050008}} PMID 8264540</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000117265'>Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 {{SGDpaper|S000117265}} PMID 16850348</ref><ref name='S000128371'>Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 {{SGDpaper|S000128371}} PMID 19013460</ref><ref name='S000148779'>Nosaka K, et al. (2012) Facilitated recruitment of Pdc2p, a yeast transcriptional activator, in response to thiamin starvation.LID - 10.1111/j.1574-6968.2012.02543.x [doi] FEMS Microbiol Lett () {{SGDpaper|S000148779}} PMID 22404710</ref><ref name='S000147201'>Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 {{SGDpaper|S000147201}} PMID </ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94
 
  {{SGDpaper|S000042760}} PMID 9055069</ref>
 
  {{SGDpaper|S000042760}} PMID 9055069</ref>
 
<br>
 
<br>
Line 23: Line 24:
 
<br>
 
<br>
 
<br>
 
<br>
−
 
+
<br>
 +
</protect>
 
__TOC__
 
__TOC__
 
==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
{{CommentaryHelp}}
  
 +
 +
 +
 +
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
 +
<!--
 +
Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
 +
<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
 +
J Biol Chem 278(5):3265-74</ref>
 +
-->
 +
 +
 +
 +
<protect>
 
==References==
 
==References==
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
<!-- REFERENCES ARE AUTOMATICALLY GENERATED.  PLEASE DON'T EDIT THIS SECTION-->
 
{{RefHelp}}
 
{{RefHelp}}
 +
</protect>

Latest revision as of 14:05, 26 March 2012

Share your knowledge...Edit this entry! <protect>

Systematic name YDR081C
Gene name PDC2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:610081..607304
Primary SGDID S000002488


Description of YDR081C: Transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; binds a DNA sequence in the PDC5 promoter; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions[1][2][3][4][5][6][7]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. ↑ Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 SGD PMID 8264540
  2. ↑ Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 SGD PMID 9655908
  3. ↑ Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 SGD PMID 16850348
  4. ↑ Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 SGD PMID 19013460
  5. ↑ Nosaka K, et al. (2012) Facilitated recruitment of Pdc2p, a yeast transcriptional activator, in response to thiamin starvation.LID - 10.1111/j.1574-6968.2012.02543.x [doi] FEMS Microbiol Lett () SGD PMID 22404710
  6. ↑ Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 SGD PMID
  7. ↑ Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94 SGD PMID 9055069

See Help:Categories on how to add the wiki page for this gene to a Category </protect>

Retrieved from "https://wiki.yeastgenome.org/index.php?title=YDR081C&oldid=363764"