Difference between revisions of "YDR081C"
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| − | '''Description of YDR081C:''' | + | '''Description of YDR081C:''' Putative transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions<ref name='S000050008'>Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 {{SGDpaper|S000050008}} PMID 8264540</ref><ref name='S000046055'>Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 {{SGDpaper|S000046055}} PMID 9655908</ref><ref name='S000117265'>Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 {{SGDpaper|S000117265}} PMID 16850348</ref><ref name='S000128371'>Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 {{SGDpaper|S000128371}} PMID 19013460</ref><ref name='S000147201'>Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 {{SGDpaper|S000147201}} PMID </ref><ref name='S000042760'>Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94 |
{{SGDpaper|S000042760}} PMID 9055069</ref> | {{SGDpaper|S000042760}} PMID 9055069</ref> | ||
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Revision as of 14:05, 27 October 2011
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| Systematic name | YDR081C |
| Gene name | PDC2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:610081..607304 |
| Primary SGDID | S000002488 |
Description of YDR081C: Putative transcription factor for thiamine-regulated genes; required for expression of the two isoforms of pyruvate decarboxylase (PDC1 and PDC5) along with thiamine biosynthetic genes; mutant fails to grow on 2% glucose and thus is scored as inviable under standard conditions[1][2][3][4][5][6]
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References
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- ↑ Hohmann S (1993) Characterisation of PDC2, a gene necessary for high level expression of pyruvate decarboxylase structural genes in Saccharomyces cerevisiae. Mol Gen Genet 241(5-6):657-66 SGD PMID 8264540
- ↑ Hohmann S and Meacock PA (1998) Thiamin metabolism and thiamin diphosphate-dependent enzymes in the yeast Saccharomyces cerevisiae: genetic regulation. Biochim Biophys Acta 1385(2):201-19 SGD PMID 9655908
- ↑ Mojzita D and Hohmann S (2006) Pdc2 coordinates expression of the THI regulon in the yeast Saccharomyces cerevisiae. Mol Genet Genomics 276(2):147-61 SGD PMID 16850348
- ↑ Nosaka K, et al. (2008) Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae. FEBS Lett 582(29):3991-6 SGD PMID 19013460
- ↑ Raghuram V, et al. (1994) PDC2, a yeast gene essential for synthesis of pyruvate decarboxylase, encodes a novel transcription factor J Genet 73():17-32 SGD PMID
- ↑ Velmurugan S, et al. (1997) Suppression of pdc2 regulating pyruvate decarboxylase synthesis in yeast. Genetics 145(3):587-94 SGD PMID 9055069
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