Difference between revisions of "YDR078C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002485 YDR078C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002485 YDR078C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHU2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SHU2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr IV:602867..602196
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|nowrap| Chr IV:602869..602198
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002485
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002485
 
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'''Description of YDR078C:''' Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p<ref name='S000123652'>Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 {{SGDpaper|S000123652}} PMID 17671161</ref><ref name='S000080406'>Shor E, et al. (2005) A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair. Genetics 169(3):1275-89 {{SGDpaper|S000080406}} PMID 15654096</ref><ref name='S000074096'>Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34
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'''Description of YDR078C:''' Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function<ref name='S000130520'>Ball LG, et al. (2009) The yeast Shu complex couples error-free post-replication repair to homologous recombination. Mol Microbiol 73(1):89-102 {{SGDpaper|S000130520}} PMID 19496932</ref><ref name='S000147390'>Bernstein KA, et al. (2011) The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Mol Biol Cell 22(9):1599-607 {{SGDpaper|S000147390}} PMID 21372173</ref><ref name='S000074096'>Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 {{SGDpaper|S000074096}} PMID 12972632</ref><ref name='S000123652'>Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 {{SGDpaper|S000123652}} PMID 17671161</ref><ref name='S000080406'>Shor E, et al. (2005) A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair. Genetics 169(3):1275-89
{{SGDpaper|S000074096}} PMID 12972632</ref>
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{{SGDpaper|S000080406}} PMID 15654096</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YDR078C
Gene name SHU2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:602869..602198
Primary SGDID S000002485


Description of YDR078C: Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function[1][2][3][4][5]




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References

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  1. Ball LG, et al. (2009) The yeast Shu complex couples error-free post-replication repair to homologous recombination. Mol Microbiol 73(1):89-102 SGD PMID 19496932
  2. Bernstein KA, et al. (2011) The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Mol Biol Cell 22(9):1599-607 SGD PMID 21372173
  3. Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 SGD PMID 12972632
  4. Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 SGD PMID 17671161
  5. Shor E, et al. (2005) A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair. Genetics 169(3):1275-89 SGD PMID 15654096

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