YDR074W

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Systematic name YDR074W
Gene name TPS2
Aliases HOG2, PFK3
Feature type ORF, Verified
Coordinates Chr IV:593890..596580
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Description of YDR074W: Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway[1][2]



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References

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  1. De Virgilio C, et al. (1993) Disruption of TPS2, the gene encoding the 100-kDa subunit of the trehalose-6-phosphate synthase/phosphatase complex in Saccharomyces cerevisiae, causes accumulation of trehalose-6-phosphate and loss of trehalose-6-phosphate phosphatase activity. Eur J Biochem 212(2):315-23 SGD PMID 8444170
  2. Winderickx J, et al. (1996) Regulation of genes encoding subunits of the trehalose synthase complex in Saccharomyces cerevisiae: novel variations of STRE-mediated transcription control? Mol Gen Genet 252(4):470-82 SGD PMID 8879249

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