YDR049W

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Systematic name YDR049W
Gene name VMS1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:553254..555152
Primary SGDID S000002456


Description of YDR049W: Zinc finger protein, forms a mitochondrially-associated complex with Cdc48p and Npl4p under oxidative stress that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD); conserved in C. elegans and human[1][2]




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References

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  1. Bohm S, et al. (1997) Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Nucleic Acids Res 25(12):2464-9 SGD PMID 9171100
  2. Heo JM, et al. (2010) A stress-responsive system for mitochondrial protein degradation. Mol Cell 40(3):465-80 SGD PMID 21070972

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