YDR017C

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Systematic name YDR017C
Gene name KCS1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:482264..479112
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Description of YDR017C: Inositol hexaphosphate kinase, phosphorylates inositol hexakisphosphate (InsP6) to diphosphoinositol polyphosphates, required for proper vacuole morphology and involved in salt stress response, contains two leucine heptad repeats[1][2]



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References

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  1. Dubois E, et al. (2002) In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem 277(26):23755-63 SGD PMID 11956213
  2. Saiardi A, et al. (2000) The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis. J Biol Chem 275(32):24686-92 SGD PMID 10827188

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