Difference between revisions of "YDR014W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002421 YDR014W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD61 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''RAD61 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr IV: | + | |nowrap| Chr IV:474046..475989 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002421 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000002421 | ||
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| − | '''Description of YDR014W:''' | + | '''Description of YDR014W:''' Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin<ref name='S000127217'>Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 {{SGDpaper|S000127217}} PMID 17113138</ref><ref name='S000127161'>Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 {{SGDpaper|S000127161}} PMID 18653893</ref><ref name='S000129839'>Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 {{SGDpaper|S000129839}} PMID 19328069</ref><ref name='S000129631'>Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 |
| − | {{SGDpaper| | + | {{SGDpaper|S000129631}} PMID 19268589</ref> |
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Latest revision as of 07:45, 23 January 2012
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| Systematic name | YDR014W |
| Gene name | RAD61 |
| Aliases | WPL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:474046..475989 |
| Primary SGDID | S000002421 |
Description of YDR014W: Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin[1][2][3][4]
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References
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- ↑ Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 SGD PMID 17113138
- ↑ Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 SGD PMID 18653893
- ↑ Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 SGD PMID 19328069
- ↑ Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 SGD PMID 19268589
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