YDL185W

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Systematic name YDL185W
Gene name TFP1
Aliases CLS8, VMA1
Feature type ORF, Verified
Coordinates Chr IV:126788..130003
Primary SGDID S000002344


Description of YDL185W: Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease[1][2][3]




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References

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  1. Shih CK, et al. (1988) A dominant trifluoperazine resistance gene from Saccharomyces cerevisiae has homology with F0F1 ATP synthase and confers calcium-sensitive growth. Mol Cell Biol 8(8):3094-103 SGD PMID 2905423
  2. Cooper AA, et al. (1993) Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision. EMBO J 12(6):2575-83 SGD PMID 8508780
  3. Hirata R, et al. (1990) Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J Biol Chem 265(12):6726-33 SGD PMID 2139027

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