YDL165W

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Systematic name YDL165W
Gene name CDC36
Aliases DNA19, NOT2
Feature type ORF, Verified
Coordinates Chr IV:164291..164866


Description of YDL165W: Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor[1][2]




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References

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  1. Russell P, et al. (2002) Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex. J Mol Biol 322(1):27-39 SGD PMID 12215412
  2. Liu HY, et al. (2001) Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J Biol Chem 276(10):7541-8 SGD PMID 11113136

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