Difference between revisions of "YDL142C"
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| − | '''Description of YDL142C:''' Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis<ref name=' | + | '''Description of YDL142C:''' Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis<ref name='S000043519'>Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41 {{SGDpaper|S000043519}} PMID 9614098</ref><ref name='S000045719'>Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 {{SGDpaper|S000045719}} PMID 10777514</ref><ref name='S000054155'>Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 {{SGDpaper|S000054155}} PMID 9987137</ref><ref name='S000074003'>Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 {{SGDpaper|S000074003}} PMID 12840009</ref><ref name='S000127786'>Chen S, et al. (2008) Cardiolipin mediates cross-talk between mitochondria and the vacuole. Mol Biol Cell 19(12):5047-58 |
| − | {{SGDpaper| | + | {{SGDpaper|S000127786}} PMID 18799619</ref> |
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Revision as of 04:15, 19 December 2008
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| Systematic name | YDL142C |
| Gene name | CRD1 |
| Aliases | CLS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:202571..201720 |
| Primary SGDID | S000002301 |
Description of YDL142C: Cardiolipin synthase; produces cardiolipin, which is a phospholipid of the mitochondrial inner membrane that is required for normal mitochondrial membrane potential and function; also required for normal vacuolar ion homeostasis[1][2][3][4][5]
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References
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- ↑ Chang SC, et al. (1998) Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae. J Biol Chem 273(24):14933-41 SGD PMID 9614098
- ↑ Jiang F, et al. (2000) Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function. J Biol Chem 275(29):22387-94 SGD PMID 10777514
- ↑ Jiang F, et al. (1999) Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development. Mol Microbiol 31(1):373-9 SGD PMID 9987137
- ↑ Zhang M, et al. (2003) Cardiolipin is not required to maintain mitochondrial DNA stability or cell viability for Saccharomyces cerevisiae grown at elevated temperatures. J Biol Chem 278(37):35204-10 SGD PMID 12840009
- ↑ Chen S, et al. (2008) Cardiolipin mediates cross-talk between mitochondria and the vacuole. Mol Biol Cell 19(12):5047-58 SGD PMID 18799619
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