Difference between revisions of "YDL101C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002259 YDL101C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002259 YDL101C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DUN1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''DUN1 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YDL101C
Gene name DUN1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:281848..280307
Primary SGDID S000002259


Description of YDL101C: Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair[1][2][3][4]




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References

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  1. Bashkirov VI, et al. (2003) Direct kinase-to-kinase signaling mediated by the FHA phosphoprotein recognition domain of the Dun1 DNA damage checkpoint kinase. Mol Cell Biol 23(4):1441-52 SGD PMID 12556502
  2. Blanchard H, et al. (2001) Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases. Acta Crystallogr D Biol Crystallogr 57(Pt 3):459-61 SGD PMID 11223532
  3. Hammet A, et al. (2002) Posttranscriptional regulation of the RAD5 DNA repair gene by the Dun1 kinase and the Pan2-Pan3 poly(A)-nuclease complex contributes to survival of replication blocks. J Biol Chem 277(25):22469-74 SGD PMID 11953437
  4. Zhao X and Rothstein R (2002) The Dun1 checkpoint kinase phosphorylates and regulates the ribonucleotide reductase inhibitor Sml1. Proc Natl Acad Sci U S A 99(6):3746-51 SGD PMID 11904430

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