YDL095W

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Systematic name YDL095W
Gene name PMT1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:287059..289512
Primary SGDID S000002253


Description of YDL095W: Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals[1][2]




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References

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  1. Strahl-Bolsinger S, et al. (1993) PMT1, the gene for a key enzyme of protein O-glycosylation in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 90(17):8164-8 SGD PMID 8367478
  2. Girrbach V and Strahl S (2003) Members of the evolutionarily conserved PMT family of protein O-mannosyltransferases form distinct protein complexes among themselves. J Biol Chem 278(14):12554-62 SGD PMID 12551906

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