Difference between revisions of "YDL089W"

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'''Description of YDL089W:''' Protein of unknown function; interacts with Csm1p, Lrs4p; required for rDNA repeat stability; null mutant causes increase in unequal sister-chromatid exchange; GFP-fusion protein localizes to the nuclear periphery, possible Cdc28p substrate<ref name='S000128279'>Mekhail K, et al. (2008) Role for perinuclear chromosome tethering in maintenance of genome stability. Nature 456(7222):667-70 {{SGDpaper|S000128279}} PMID 18997772</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
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'''Description of YDL089W:''' Protein of unknown function; interacts with Csm1p, Lrs4p; required for rDNA repeat stability; null mutant causes increase in unequal sister-chromatid exchange; GFP-fusion protein localizes to the nuclear periphery, possible Cdc28p substrate<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000128279'>Mekhail K, et al. (2008) Role for perinuclear chromosome tethering in maintenance of genome stability. Nature 456(7222):667-70
  {{SGDpaper|S000074185}} PMID 14562095</ref>
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  {{SGDpaper|S000128279}} PMID 18997772</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YDL089W
Gene name NUR1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:296820..298274
Primary SGDID S000002247


Description of YDL089W: Protein of unknown function; interacts with Csm1p, Lrs4p; required for rDNA repeat stability; null mutant causes increase in unequal sister-chromatid exchange; GFP-fusion protein localizes to the nuclear periphery, possible Cdc28p substrate[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Mekhail K, et al. (2008) Role for perinuclear chromosome tethering in maintenance of genome stability. Nature 456(7222):667-70 SGD PMID 18997772
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-21

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