YDL079C

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Systematic name YDL079C
Gene name MRK1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:314748..312951
Primary SGDID S000002237


Description of YDL079C: Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [4] [5]





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References

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  1. Andoh T, et al. (2000) Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5. Mol Cell Biol 20(18):6712-20 SGD PMID 10958669
  2. Hardy TA, et al. (1995) Novel Saccharomyces cerevisiae gene, MRK1, encoding a putative protein kinase with similarity to mammalian glycogen synthase kinase-3 and Drosophila Zeste-White3/Shaggy. Biochem Biophys Res Commun 208(2):728-34 SGD PMID 7695629
  3. Hirata Y, et al. (2003) Yeast glycogen synthase kinase-3 activates Msn2p-dependent transcription of stress responsive genes. Mol Biol Cell 14(1):302-12 SGD PMID 12529445
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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