YDL040C

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Systematic name YDL040C
Gene name NAT1
Aliases AAA1, NAA15
Feature type ORF, Verified
Coordinates Chr IV:381435..378871
Primary SGDID S000002198


Description of YDL040C: Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing[1][2][3][4]




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References

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  1. Park EC and Szostak JW (1992) ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J 11(6):2087-93 SGD PMID 1600941
  2. Mullen JR, et al. (1989) Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast. EMBO J 8(7):2067-75 SGD PMID 2551674
  3. Polevoda B and Sherman F (2003) Composition and function of the eukaryotic N-terminal acetyltransferase subunits. Biochem Biophys Res Commun 308(1):1-11 SGD PMID 12890471
  4. Gautschi M, et al. (2003) The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides. Mol Cell Biol 23(20):7403-14 SGD PMID 14517307

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