Difference between revisions of "YDL033C"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr IV:393909..392656 | |nowrap| Chr IV:393909..392656 | ||
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 08:17, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YDL033C |
| Gene name | SLM3 |
| Aliases | MTO2, MTU1 |
| Feature type | ORF, Uncharacterized |
| Coordinates | Chr IV:393909..392656 |
Description of YDL033C: tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)[1][2]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Yan Q, et al. (2005) Mutations in MTO2 related to tRNA modification impair mitochondrial gene expression and protein synthesis in the presence of a paromomycin resistance mutation in mitochondrial 15 S rRNA. J Biol Chem 280(32):29151-7 SGD PMID 15944150
- ↑ Umeda N, et al. (2005) Mitochondria-specific RNA-modifying enzymes responsible for the biosynthesis of the wobble base in mitochondrial tRNAs. Implications for the molecular pathogenesis of human mitochondrial diseases. J Biol Chem 280(2):1613-24 SGD PMID 15509579
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
