YDL022W

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Systematic name YDL022W
Gene name GPD1
Aliases DAR1, HOR1, OSG1, OSR5
Feature type ORF, Verified
Coordinates Chr IV:411825..413000
Primary SGDID S000002180


Description of YDL022W: NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p[1][2]




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References

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  1. Albertyn J, et al. (1994) GPD1, which encodes glycerol-3-phosphate dehydrogenase, is essential for growth under osmotic stress in Saccharomyces cerevisiae, and its expression is regulated by the high-osmolarity glycerol response pathway. Mol Cell Biol 14(6):4135-44 SGD PMID 8196651
  2. Nevoigt E and Stahl U (1996) Reduced pyruvate decarboxylase and increased glycerol-3-phosphate dehydrogenase [NAD+] levels enhance glycerol production in Saccharomyces cerevisiae. Yeast 12(13):1331-7 SGD PMID 8923738

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