YDL010W

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Systematic name YDL010W
Gene name GRX6
Aliases
Feature type ORF, Verified
Coordinates Chr IV:432327..433022
Primary SGDID S000002168


Description of YDL010W: Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; functional overlap with GRX6[1][2][3][4][5]




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References

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  1. Jump up Mesecke N, et al. (2008) A Novel Group of Glutaredoxins in the cis-Golgi Critical for Oxidative Stress Resistance. Mol Biol Cell SGD PMID 18400945
  2. Jump up Mesecke N, et al. (2008) Two Novel Monothiol Glutaredoxins from Saccharomyces cerevisiae Provide Further Insight into Iron-Sulfur Cluster Binding, Oligomerization, and Enzymatic Activity of Glutaredoxins. Biochemistry 47(5):1452-63 SGD PMID 18171082
  3. Jump up Herrero E and Izquierdo A (2007) SGD PMID
  4. Jump up Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  5. Jump up Fetrow JS, et al. (2001) Genomic-scale comparison of sequence- and structure-based methods of function prediction: does structure provide additional insight? Protein Sci 10(5):1005-14 SGD PMID 11316881

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