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Systematic name YDL010W
Gene name GRX6
Feature type ORF, Verified
Coordinates Chr IV:432327..433022
Primary SGDID S000002168

Description of YDL010W: Monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; forms homodimers; green fluorescent protein (GFP)-fusion protein localizes to the vacuole[1][2][3][4]


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  1. Mesecke N, et al. (2008) Two Novel Monothiol Glutaredoxins from Saccharomyces cerevisiae Provide Further Insight into Iron-Sulfur Cluster Binding, Oligomerization, and Enzymatic Activity of Glutaredoxins. Biochemistry 47(5):1452-63 SGD PMID 18171082
  2. Herrero E and Izquierdo A (2007) SGD PMID
  3. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  4. Fetrow JS, et al. (2001) Genomic-scale comparison of sequence- and structure-based methods of function prediction: does structure provide additional insight? Protein Sci 10(5):1005-14 SGD PMID 11316881

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