Difference between revisions of "YDL006W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YDL006W YDL006W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000002164 YDL006W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PTC1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PTC1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr IV:439906..440751
 
|nowrap| Chr IV:439906..440751
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000002164
 
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'''Description of {{PAGENAME}}:''' Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation<ref name='S000059233'>Warmka J, et al. (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol 21(1):51-60 {{SGDpaper|S000059233}} PMID 11113180</ref><ref name='S000051463'>Roeder AD, et al. (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 9(4):917-30 {{SGDpaper|S000051463}} PMID 9529388</ref><ref name='S000048289'>Maeda T, et al. (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369(6477):242-5 {{SGDpaper|S000048289}} PMID 8183345</ref><ref name='S000041090'>van Zyl WH, et al. (1989) A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123(1):55-68 {{SGDpaper|S000041090}} PMID 2680757</ref><ref name='S000040961'>Robinson MK, et al. (1994) TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol 14(6):3634-45
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'''Description of YDL006W:''' Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation<ref name='S000059233'>Warmka J, et al. (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol 21(1):51-60 {{SGDpaper|S000059233}} PMID 11113180</ref><ref name='S000051463'>Roeder AD, et al. (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 9(4):917-30 {{SGDpaper|S000051463}} PMID 9529388</ref><ref name='S000048289'>Maeda T, et al. (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369(6477):242-5 {{SGDpaper|S000048289}} PMID 8183345</ref><ref name='S000041090'>van Zyl WH, et al. (1989) A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123(1):55-68 {{SGDpaper|S000041090}} PMID 2680757</ref><ref name='S000040961'>Robinson MK, et al. (1994) TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol 14(6):3634-45
 
  {{SGDpaper|S000040961}} PMID 8196609</ref>
 
  {{SGDpaper|S000040961}} PMID 8196609</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YDL006W
Gene name PTC1
Aliases CWH47, KCS2, TPD1
Feature type ORF, Verified
Coordinates Chr IV:439906..440751
Primary SGDID S000002164


Description of YDL006W: Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation[1][2][3][4][5]




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References

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  1. Warmka J, et al. (2001) Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol 21(1):51-60 SGD PMID 11113180
  2. Roeder AD, et al. (1998) Mitochondrial inheritance is delayed in Saccharomyces cerevisiae cells lacking the serine/threonine phosphatase PTC1. Mol Biol Cell 9(4):917-30 SGD PMID 9529388
  3. Maeda T, et al. (1994) A two-component system that regulates an osmosensing MAP kinase cascade in yeast. Nature 369(6477):242-5 SGD PMID 8183345
  4. van Zyl WH, et al. (1989) A general screen for mutant of Saccharomyces cerevisiae deficient in tRNA biosynthesis. Genetics 123(1):55-68 SGD PMID 2680757
  5. Robinson MK, et al. (1994) TPD1 of Saccharomyces cerevisiae encodes a protein phosphatase 2C-like activity implicated in tRNA splicing and cell separation. Mol Cell Biol 14(6):3634-45 SGD PMID 8196609

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