YCR094W

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Systematic name YCR094W
Gene name CDC50
Aliases
Feature type ORF, Verified
Coordinates Chr III:286759..287934
Primary SGDID S000000690


Description of YCR094W: Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Ynr048wp and Lem3p[1][2][3][4]




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References

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  1. Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 SGD PMID 11180453
  2. Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32 SGD PMID 15090616
  3. Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 SGD PMID 12589066
  4. Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67 SGD PMID 19411703

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