YCR084C
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| Systematic name | YCR084C | |
| Gene name | TUP1 | |
| Aliases | AAR1, AER2, AMM1, CRT4, CYC9, FLK1, ROX4, SFL2, UMR7 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr III:262449..260308 | |
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Description of YCR084C: General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes[1][2][3][4][5][6]
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References
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- ↑ Conlan RS, et al. (1999) The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator. J Biol Chem 274(1):205-10 SGD PMID 9867831
- ↑ Keleher CA, et al. (1992) Ssn6-Tup1 is a general repressor of transcription in yeast. Cell 68(4):709-19 SGD PMID 1739976
- ↑ Zhang L and Guarente L (1994) Evidence that TUP1/SSN6 has a positive effect on the activity of the yeast activator HAP1. Genetics 136(3):813-7 SGD PMID 8005436
- ↑ Williams FE, et al. (1991) The CYC8 and TUP1 proteins involved in glucose repression in Saccharomyces cerevisiae are associated in a protein complex. Mol Cell Biol 11(6):3307-16 SGD PMID 2038333
- ↑ Cooper JP, et al. (1994) The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev 8(12):1400-10 SGD PMID 7926740
- ↑ Edmondson DG, et al. (1996) Repression domain of the yeast global repressor Tup1 interacts directly with histones H3 and H4. Genes Dev 10(10):1247-59 SGD PMID 8675011
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