YCR079W

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Systematic name YCR079W
Gene name PTC6
Aliases AUP1
Feature type ORF, Verified
Coordinates Chr III:252842..254170
Primary SGDID S000002133


Description of YCR079W: Phosphoprotein phosphatase type 2C similar to mammalian PP1Ks; involved in mitophagy; localized to mitochondrial inner membrane space; null mutant is sensitive to rapamycin[1][2][3][4]




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References

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  1. Tal R, et al. (2007) Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J Biol Chem 282(8):5617-24 SGD PMID 17166847
  2. Ruan H, et al. (2007) The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae. FEMS Yeast Res 7(2):209-15 SGD PMID 17002782
  3. Tomaska L (2000) Mitochondrial protein phosphorylation: lessons from yeasts. Gene 255(1):59-64 SGD PMID 10974565
  4. Sakumoto N, et al. (1999) A series of protein phosphatase gene disruptants in Saccharomyces cerevisiae. Yeast 15(15):1669-79 SGD PMID 10572263

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