YCR068W

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Systematic name YCR068W
Gene name ATG15
Aliases AUT5, CVT17
Feature type ORF, Verified
Coordinates Chr III:237210..238772
Primary SGDID S000000664


Description of YCR068W: Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway[1][2]




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References

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  1. Epple UD, et al. (2003) Intravacuolar membrane lysis in Saccharomyces cerevisiae. Does vacuolar targeting of Cvt17/Aut5p affect its function? J Biol Chem 278(10):7810-21 SGD PMID 12499386
  2. Epple UD, et al. (2001) Aut5/Cvt17p, a putative lipase essential for disintegration of autophagic bodies inside the vacuole. J Bacteriol 183(20):5942-55 SGD PMID 11566994

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