Difference between revisions of "YCR066W"

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'''Description of YCR066W:''' E3 ubiqutin ligase, forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair<ref name='S000051450'>Bailly V, et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272(37):23360-5 {{SGDpaper|S000051450}} PMID 9287349</ref><ref name='S000131245'>Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9
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'''Description of YCR066W:''' E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair<ref name='S000051450'>Bailly V, et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272(37):23360-5 {{SGDpaper|S000051450}} PMID 9287349</ref><ref name='S000131245'>Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9
 
  {{SGDpaper|S000131245}} PMID 19217833</ref>
 
  {{SGDpaper|S000131245}} PMID 19217833</ref>
 
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Revision as of 14:05, 10 April 2012

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Systematic name YCR066W
Gene name RAD18
Aliases
Feature type ORF, Verified
Coordinates Chr III:231500..232963
Primary SGDID S000000662


Description of YCR066W: E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair[1][2]




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References

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  1. Bailly V, et al. (1997) Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities. J Biol Chem 272(37):23360-5 SGD PMID 9287349
  2. Ulrich HD (2009) Regulating post-translational modifications of the eukaryotic replication clamp PCNA. DNA Repair (Amst) 8(4):461-9 SGD PMID 19217833

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