Difference between revisions of "YCR057C"

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Revision as of 08:20, 23 January 2007

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Systematic name YCR057C
Gene name PWP2
Aliases UTP1, YCR055C, YCR058C
Feature type ORF, Verified
Coordinates Chr III:223224..220453
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Description of YCR057C: Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis[1][2]



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References

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  1. Dosil M and Bustelo XR (2004) Functional characterization of Pwp2, a WD family protein essential for the assembly of the 90 S pre-ribosomal particle. J Biol Chem 279(36):37385-97 SGD PMID 15231838
  2. Shafaatian R, et al. (1996) PWP2, a member of the WD-repeat family of proteins, is an essential Saccharomyces cerevisiae gene involved in cell separation. Mol Gen Genet 252(1-2):101-14 SGD PMID 8804409

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