Difference between revisions of "YCR002C"
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| − | '''Description of YCR002C:''' Component of the septin ring that is required for cytokinesis; septins | + | '''Description of YCR002C:''' Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus contributes septin interaction with phosphatidylinositol-4,5-bisphosphate<ref name='S000138568'>Bertin A, et al. (2010) Phosphatidylinositol-4,5-bisphosphate Promotes Budding Yeast Septin Filament Assembly and Organization. J Mol Biol 404(4):711-31 {{SGDpaper|S000138568}} PMID 20951708</ref><ref name='S000074161'>Gladfelter AS, et al. (2001) The septin cortex at the yeast mother-bud neck. Curr Opin Microbiol 4(6):681-9 {{SGDpaper|S000074161}} PMID 11731320</ref><ref name='S000074229'>Hanrahan J and Snyder M (2003) Cytoskeletal activation of a checkpoint kinase. Mol Cell 12(3):663-73 {{SGDpaper|S000074229}} PMID 14527412</ref><ref name='S000145157'>McMurray MA, et al. (2011) Septin filament formation is essential in budding yeast. Dev Cell 20(4):540-9 {{SGDpaper|S000145157}} PMID 21497764</ref><ref name='S000059701'>Takizawa PA, et al. (2000) Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science 290(5490):341-4 {{SGDpaper|S000059701}} PMID 11030653</ref><ref name='S000077562'>Versele M, et al. (2004) Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Mol Biol Cell 15(10):4568-83 {{SGDpaper|S000077562}} PMID 15282341</ref><ref name='S000121415'>Vrabioiu AM, et al. (2004) The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J Biol Chem 279(4):3111-8 {{SGDpaper|S000121415}} PMID 14597621</ref><ref name='S000146330'>Wloka C, et al. (2011) Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast. Biol Chem 392(8-9):813-829 |
{{SGDpaper|S000146330}} PMID 21824009</ref> | {{SGDpaper|S000146330}} PMID 21824009</ref> | ||
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Revision as of 14:05, 11 October 2011
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| Systematic name | YCR002C |
| Gene name | CDC10 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:118348..117380 |
| Primary SGDID | S000000595 |
Description of YCR002C: Component of the septin ring that is required for cytokinesis; septins are GTP-binding proteins that assemble into rod-like hetero-oligomers that can associate with other rods to form filaments; septin rings at the mother-bud neck act as scaffolds for recruiting cell division factors and as barriers to prevent diffusion of specific proteins between mother and daughter cells; N-terminus contributes septin interaction with phosphatidylinositol-4,5-bisphosphate[1][2][3][4][5][6][7][8]
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References
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- ↑ Bertin A, et al. (2010) Phosphatidylinositol-4,5-bisphosphate Promotes Budding Yeast Septin Filament Assembly and Organization. J Mol Biol 404(4):711-31 SGD PMID 20951708
- ↑ Gladfelter AS, et al. (2001) The septin cortex at the yeast mother-bud neck. Curr Opin Microbiol 4(6):681-9 SGD PMID 11731320
- ↑ Hanrahan J and Snyder M (2003) Cytoskeletal activation of a checkpoint kinase. Mol Cell 12(3):663-73 SGD PMID 14527412
- ↑ McMurray MA, et al. (2011) Septin filament formation is essential in budding yeast. Dev Cell 20(4):540-9 SGD PMID 21497764
- ↑ Takizawa PA, et al. (2000) Plasma membrane compartmentalization in yeast by messenger RNA transport and a septin diffusion barrier. Science 290(5490):341-4 SGD PMID 11030653
- ↑ Versele M, et al. (2004) Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Mol Biol Cell 15(10):4568-83 SGD PMID 15282341
- ↑ Vrabioiu AM, et al. (2004) The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides. J Biol Chem 279(4):3111-8 SGD PMID 14597621
- ↑ Wloka C, et al. (2011) Evidence that a septin diffusion barrier is dispensable for cytokinesis in budding yeast. Biol Chem 392(8-9):813-829 SGD PMID 21824009
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