YBR253W

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Systematic name YBR253W
Gene name SRB6
Aliases MED22
Feature type ORF, Verified
Coordinates Chr II:723265..723630
Primary SGDID S000000457


Description of YBR253W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation[1][2][3]




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References

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  1. Thompson CM, et al. (1993) A multisubunit complex associated with the RNA polymerase II CTD and TATA-binding protein in yeast. Cell 73(7):1361-75 SGD PMID 8324825
  2. Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
  3. Takagi Y, et al. (2006) Head module control of mediator interactions. Mol Cell 23(3):355-64 SGD PMID 16885025

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