YBR252W

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Systematic name YBR252W
Gene name DUT1
Aliases
Feature type ORF, Verified
Coordinates Chr II:722606..723049
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Description of YBR252W: dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability[1][2][3]



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References

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  1. Guillet M, et al. (2006) dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae. Nucleic Acids Res 34(7):2056-66 SGD PMID 16617146
  2. Godsen, M.H, et al. (1986) The isolation of dUTPase gene (DUT1) from Saccharomyces cerevisiae. Yeast 2:121 SGD PMID
  3. Gadsden MH, et al. (1993) dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae. EMBO J 12(11):4425-31 SGD PMID 8223452

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