Difference between revisions of "YBR252W"
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| − | '''Description of YBR252W:''' dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability<ref name=' | + | '''Description of YBR252W:''' dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability<ref name='S000051873'>Gadsden MH, et al. (1993) dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae. EMBO J 12(11):4425-31 {{SGDpaper|S000051873}} PMID 8223452</ref><ref name='S000058548'>Godsen, M.H, et al. (1986) The isolation of dUTPase gene (DUT1) from Saccharomyces cerevisiae. Yeast 2:121 {{SGDpaper|S000058548}} PMID </ref><ref name='S000115090'>Guillet M, et al. (2006) dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae. Nucleic Acids Res 34(7):2056-66 |
| − | {{SGDpaper| | + | {{SGDpaper|S000115090}} PMID 16617146</ref> |
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Revision as of 04:40, 18 December 2008
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| Systematic name | YBR252W |
| Gene name | DUT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr II:722606..723049 |
| Primary SGDID | S000000456 |
Description of YBR252W: dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability[1][2][3]
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References
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- ↑ Gadsden MH, et al. (1993) dUTP pyrophosphatase is an essential enzyme in Saccharomyces cerevisiae. EMBO J 12(11):4425-31 SGD PMID 8223452
- ↑ Godsen, M.H, et al. (1986) The isolation of dUTPase gene (DUT1) from Saccharomyces cerevisiae. Yeast 2:121 SGD PMID
- ↑ Guillet M, et al. (2006) dUTPase activity is critical to maintain genetic stability in Saccharomyces cerevisiae. Nucleic Acids Res 34(7):2056-66 SGD PMID 16617146
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